Wulan Deng Lab

Publications

(Google Scholar Profile  https://scholar.google.com/citations?user=k2WhDwUAAAAJ&hl=en)

  1. Wang, Zuhui, and Wulan Deng. Dynamic Transcription Regulation at the Single-Molecule Level.(2022) Developmental Biology 482: 67–81. https://doi.org/10.1016/j.ydbio.2021.11.004.
  2. Wulan Deng, and Gerd A. Blobel. Detecting Long-Range Enhancer-Promoter Interactions by Quantitative Chromosome Conformation Capture. (2017) Methods Mol Biol. 1468:51-62.
  3. Laura Breda, Irene Motta, Silvia Lourenco, Chiara Gemmo, Wulan Deng, Jeremy W. Rupon, Osheiza Y. Abdulmalik, Deepa Manwani*, Gerd A. Blobel*, and Stefano Rivella. Forced chromatin looping raises fetal hemoglobin in adult sickle cells to higher levels than pharmacologic inducers. (2016) Blood. pii: blood-2016-01-691089.
  4. Spencer C. Knight, Liangqi Xie, Wulan Deng, Benjamin Guglielmi, Lea B. Witkowsky, Lana Bosanac, Elisa T. Zhang, Mohamed El Beheiry, Jean-Baptiste Masson, Maxime Dahan, Zhe Liu *, Jennifer A. Doudna* and * Robert Tjian*. Dynamics of CRISPR-Cas9 Genome Interrogation in Living Cells.(2015) Science, 350(6262):823-6
  5. Wulan Deng*, Xinghua Shi, Robert Tjian, Timothée Lionnet, and Robert H. Singer*. CASFISH: CRISPR/Cas9 Mediated in situ Labeling of Genomic Loci in Fixed Cells. (2015) Proceedings of the National Academy of Sciences. 112(38):11870-5. Epub 2015 Aug 31.
  6. Wulan Deng#, Jeremy W. Rupon#, Ivan Krivega, Laura Breda, Irene Motta, Kristen S. Jahn, Andreas Reik, Philip D.Gregory, StefanoRivella, Ann Dean, Gerd A.Blobel. (2014) Reactivation of developmentally silenced globin genes by forced chromatin looping. Cell, 158(4):849-60.  
  7. Wulan Deng, Jeremy W Rupon, Hongxin Wang, Andreas Reik, Philip D Gregory, and Gerd A Blobel (2013) Controlling long-range genomic interactions to reprogram the β-globin locus. Epigenetics & Chromatin. 6(Suppl 1): O39.
  8. Wulan Deng, Gerd A Blobel. Manipulating nuclear architecture. (2014) Curr Opin Genet Dev. 25:1-7. Epub 2013 Dec 12. Review.
  9. Mouse ENCODE Consortium; John A Stamatoyannopoulos, Michael Snyder, Ross Hardison, Bing Ren, Thomas Gingeras, David M Gilbert, Mark Groudine, Michael Bender, Rajinder Kaul, Theresa Canfield, Erica Giste, Audra Johnson, Mia Zhang, Gayathri Balasundaram, Rachel Byron, Vaughan Roach, Peter J Sabo, Richard Sandstrom, A Sandra Stehling, Robert E Thurman, Sherman M Weissman, Philip Cayting, Manoj Hariharan, Jin Lian, Yong Cheng, Stephen G Landt, Zhihai Ma, Barbara J Wold, Job Dekker, Gregory E Crawford, Cheryl A Keller, Weisheng Wu, Christopher Morrissey, Swathi A Kumar, Tejaswini Mishra, Deepti Jain, Marta Byrska-Bishop, Daniel Blankenberg, Bryan R Lajoie, Gaurav Jain, Amartya Sanyal, Kaun-Bei Chen, Olgert Denas, James Taylor, Gerd A Blobel, Mitchell J Weiss, Max Pimkin, Wulan Deng, Georgi K Marinov, Brian A Williams, Katherine I Fisher-Aylor, Gilberto Desalvo, Anthony Kiralusha, Diane Trout, Henry Amrhein, Ali Mortazavi, Lee Edsall, David McCleary, Samantha Kuan, Yin Shen, Feng Yue, Zhen Ye, Carrie A Davis, Chris Zaleski, Sonali Jha, Chenghai Xue, Alex Dobin, Wei Lin, Meagan Fastuca, Huaien Wang, Roderic Guigo, Sarah Djebali, Julien Lagarde, Tyrone Ryba, Takayo Sasaki, Venkat S Malladi, Melissa S Cline, Vanessa M Kirkup, Katrina Learned, Kate R Rosenbloom, W James Kent, Elise A Feingold, Peter J Good, Michael Pazin, Rebecca F Lowdon, Leslie B Adams. (2012) Genome Biol. 13(8):418.
  10. Wulan Deng, Jongjoo Lee, Hongxin Wang, Jeff Miller, Andreas Reik, Philip D Gregory, Ann Dean, Gerd A Blobel. (2012) Controlling long range genomic interactions at a native locus by targeted tethering of a looping factor. Cell, 149(6):1233-44.
    (Featured by Cell PaperFlick    http://www.cell.com/abstract/S0092-8674(12)00588-0)
  11. Janine M Lamonica, Wulan Deng, Stephan Kadauke, Amy E Campbell, Roland Gamsjaeger, Hongxin Wang, Yong Cheng, Andrew N Billin, Ross C Hardison, Joel P Mackay, Gerd A Blobel. (2011) Bromodomain protein Brd3 associates with acetylated GATA1 to promote its chromatin occupancy at erythroid target genes. Proc Natl Acad Sci U S A. 108(22):E159-68.
  12. Wulan Deng, Gerd A Blobel. Do chromatin loops provide epigenetic gene expression states? (2010) Curr Opin Genet Dev. 20(5):548-54. Epub 2010 Jul 1. Review.
  13. Yong Cheng, Weisheng Wu, Swathi Ashok Kumar, Duonan Yu, Wulan Deng, Tamara Tripic, David C King, Kuan-Bei Chen, Ying Zhang, Daniela Drautz, Belinda Giardine, Stephan C Schuster, Webb Miller, Francesca Chiaromonte, Yu Zhang, Gerd A Blobel, Mitchell J Weiss, Ross C Hardison. Erythroid GATA1 function revealed by genome-wide analysis of transcription factor occupancy, histone modifications, and mRNA expression. (2009) Genome Res. 19(12):2172-84.
  14. Tamara Tripic#, Wulan Deng#, Yong Cheng, Ying Zhang, Christopher R Vakoc, Gregory D Gregory, Ross C Hardison, Gerd A Blobel. (2009) SCL and associated proteins distinguish active from repressive GATA transcription factor complexes. Blood. 113(10):2191-201.
  15. Feng Zhou, Yingying Pu, Taiyun Wei, Huijun Liu, Wulan Deng, Chunhong Wei, Biao Ding, Toshihiro Omura, Yi Li. The P2 capsid protein of the nonenveloped rice dwarf phytoreovirus induces membrane fusion in insect host cells. (2008) Proc Natl Acad Sci U S A.105(4):1386
  16. Feng Zhou, Gang Wu, Wulan Deng, Yingying Pu, Chunhong Wei, Yi Li. Interaction of rice dwarf virus outer capsid P8 protein with rice glycolate oxidase mediates relocalization of P8. (2007) FEBS Lett. 581(1):34-40.

Patents

  1. Controlled gene expression methods.
    Publication number: WO2013184197 A1, CA2875945A1, EP2858680A1, EP2858680A4, US20150152151
    Inventors: Gerd A. Blobel, Wulan Deng
  2. Genomic probes.
    Publication number: WO2016061523 A1
    Inventors: Robert H. Singer, Wulan Deng, Timothee Lionnet
  3. Viral vectors for prophylaxis and therapy of hemoglobinopathies.
    Publication number: WO2016118715 A1
    Inventors: Stefano Rivella, Laura Breda, Alisa Dong, Gerd Blobel, Wulan Deng